To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
Within the Institute, the "Funding Research and Technology Transfer" team is at your disposal to identify the scientists and the skills you need to set up a joint project, to define the terms of a collaboration contract or study.
Whether you are an academic, a SME or an industrialist, our team informs and advices you about the possibilities of consortium assembly, technology transfer, patent licensing or use of our platforms.
The team is also at the disposal of the researchers of the institute to accompany them in achieving their valorization objectives.
All the news of the Institute of life sciences Frédéric Joliot
A NeuroSpin team showed that the mere short-term storage of information may proceed without consciousness or persistent neural activity, but that manipulating information in working memory requires both. This study, thereby reconciling a hotly debated topic in the field of neuroscience, was published in PNAS.
Researchers from I2BC@Saclay, the University of Aarhus and the Max Planck Institute of Biophysics in Frankfurt reveals the first cryo-EM high-resolution structures of one of the P4-ATPases. Study has been published in Nature. It give a better insight towards the understanding of the transport mechanisms of membrane lipids. A lipid pathway through the protein membrane domain is suggested.
A collaboration between teams from SIMOPRO and Sanofi sheds new light on the origin of the immune responses developed by patients with scleroderma when treated by injection of relaxin, a therapeutic protein. The study was published in The Journal of Immunology.
Imaging the brain of a patient at the microscopic scale is as of yet not possible but might turn into a reality thanks to a new tool for creating virtual biopsies. This algorithm has been developed by a team of NeuroSpin (CEA-Joliot) in collaboration with the Institute of NeuroScience and Medicine of Juelich as part of the European Human Brain Project. A first study demontrsating the potentiel of the algorithm ot simulate white matter samples has been published in NeuroImage.
Researchers from Inserm, in collaboration with a team from NeuroSpin, have developed a preparation to observe sequentially the neuronal activity and vascular responses of the same mouse with bi-photonic microscopy, ultrasound imaging and BOLD-fMRI, in response to an olfactory stimulus. This approach made it possible to quantitatively compare the responses to odors observed both at the microscopic and mesoscopic scales. Results, published in Nat. Comm, show that the three techniques similarly measure the concentration of an odor.
Plants, algae, cyanobacteria regulate their photosynthesis so that it is as effective as possible and not deleterious. A sutdy led by a SB2SM team unveils one of the mechanisms of regulation in cyanobacteria and show that it is very different from that equivalent in plants and algae.
A team from the SCBM, in collaboration with the SPI, the IC2MP and the University Hospital of Poitiers, has developed a bioorthogonal chemistry strategy that allows, in vivo, the controlled release of active ingredients contained in micelles-targeting cancerous tumors. These results pave the way for new strategies for targeted drug delivery.
Very high-resolution MRI will provide particularly detailed images of the brain. However, the acquisition times of MRI data strongly increase with resolution. To solve this problem, the mathematicians at NeuroSpin have developed an algorithm that allows to gain a factor of 20 !
A collaboration between SIMOPRO, Sanofi R & D, Smartox Laboratories and the Thorax Institute, has isolated a toxin with antinociceptive properties from a high-throughput electrophysiological screening of a collection of more than 100 venoms. Cyriotoxin-1a has been identified, sequenced, chemically synthesized and functionally characterized - from cell to organism in vivo.
Facilitating the deuterium and tritium labeling of molecules containing nucleic bases such as many compounds of pharmacological interest? This is what researchers from SCBM in partnership with teams from SPI and Toulouse managed to achieve.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.