To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
Within the Institute, the "Funding Research and Technology Transfer" team is at your disposal to identify the scientists and the skills you need to set up a joint project, to define the terms of a collaboration contract or study.
Whether you are an academic, a SME or an industrialist, our team informs and advices you about the possibilities of consortium assembly, technology transfer, patent licensing or use of our platforms.
The team is also at the disposal of the researchers of the institute to accompany them in achieving their valorization objectives.
All the news of the Institute of life sciences Frédéric Joliot
Why are we aware of certain visual stimuli and not others? An international study, involving Stanislas Dehaene's group from NeuroSpin, provides answers.
Cell biology uses fluorescent labeling, an essential technique to follow the life of the cell. But fluorescent proteins have their limits, which researchers from IBS and I2BC @ Saclay (SB2SM) are trying to repel.
Researchers from SCBM, in collaboration with Paris-Sud University and INSA Toulouse, developed the first general method for tritium and deuterium labeling of complex molecules with thioether-type motifs (including sulfur atom). This method allows rapid access to tritiated or deuterated molecules used in the pharmaceutical industry for in vivo monitoring or the biological assay of substances of interest.
Two Research Teams from SIMOPRO and SCBM, in collaboration with Texas Biomedical Research Institute and Jilin University, showed that anti-ricin compounds Retro-2, discovered at CEA during researches against bioterrorism, inhibit two families of viruses important for public health (Ebola and Marburg filovirus and enterovirus EV71). These results broaden the antiviral spectrum of Retro-2 type compounds.
Misspelled WordNeuroSpin researchers, in collaboration with two German Research Teams in the context of the Human Brain Project (HBP), offer a mapping of the hippocampus with unprecedented resolution, thanks to the very high field MRI, revealing not only its sub-structures, but also its internal neuronal connections and its cellular composition.
Researchers from NeuroSpin (UNICOG) highlighted how the specific region of word recognition develops during the process of learning to read among children during first grade. This work, which helped to locate a "mailbox" in the left hemisphere, was published in the journal PLOS Biology and was the subject of a press release on March 13, 2018.
Muriel Gondry's Research Team (I2BC@Saclay / SBIGeM), in collaboration with SIMOPRO and Biomolecules Laboratory of the Sorbonne University's one, produced 200 cyclodipeptides containing non-natural amino acids by luring and diverting the cellular machinery for the synthesis of proteins. This unprecedented approach significantly increases the diversity of these bioactive molecules.
Research Teams from SHFJ, MIRCen and NeuroSpin tested a pharmacokinetic analysis model of Positron-emission tomography (PET) data at 18F-DPA-714, taking into account endothelial cell activity not specifically associated with an inflammatory state. This model allows a more precise interpretation of PET images of neuroinflammation present in most neurodegenerative pathologies.
A Research Team from I2BC@Saclay (SB2SM), in collaboration with ISMO and ICMMO teams (CNRS / Univ.Paris-Sud, Univ.Paris-Saclay) measured accumulation kinetics of electrical charges within a molecular system designed for studies on artificial photosynthesis. These works, published in Angewandte Chemie, show for the first time the second electron of this fundamental process about the conversion of light energy into fuel.
Researchers from NeuroSpin (Frédéric Joliot Institute/CEA) and MIRCen (François Jacob Institute/CEA Institute of Biology) have just developed an ultrasound device guided by magnetic resonance imaging (MRI) to increase temporarily and locally the vascular permeability in non-human primates, which could be used to effectively deliver drugs to the brain.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.