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Laboratory | Chemistry


SCBM

Analysis group

 

​​FRENCH

 

Published on 27 June 2018
Our group collaborates with the synthetic chemists of the different groups of SCBM and IBITECS. The missions of our group consist in the set-up and realization of small- to large-scale purification processes followed by a detailed analysis of organic molecules prepared by chemists from SCBM. For this purpose, different techniques are routinely used: HPLC, Mass spectrometry, NMR, UV and IR spectroscopy.

Team Leader
David Buisson
01 69 08 66 38
david.buisson@cea.fr

Staff

David-Alexandre Buisson, Engineer
Céline Puente, Research Technician

 

Types of analyses

HPLC separation applied to
  •  Titration
  • Enantiomeric excess measurement
  • Purification
     
Structure elucidation /Caracterization
Radioactive activity measurement
 Mass Spectrometry

 

 

 

 

 

 

 Purification

Techniques and equipment

NMR 400 MHz Bruker Avance Spectrometer
  • broad band probe:
    RMN 1D et 2D 1H, 13C, 31P, 11B, 15N…
  • 19F probe
  • 3H probe 
UV and IR-TF Spectrometer
Liquid scintillation counter
Activity measurement
(14C, 3H, 125I)
Mass spectrometer (ESI/TOF)
  • Structure elucidation 
  • Characterization
  • Isotopic enrichment of labeled compounds
HPLC analytic pumps/UV/PDA/MS detector
  • Reverse and normal phase chromatography conditions settling
  • Titration
  • Enantiomeric excess measurement (chiral phases)
Autopurify Waters systems

HPLC analytic/preparative pumps equipped with automatic sampler-fraction collector/UV-PDA/MS Detection

  • Reverse and normal phase chromatography conditions settling
  • Scale-up, purification up to 1g  
Radioactive HPLC analytic equipped with Alliance System and ZQ/UV-PDA Detection
  •  Reverse and normal phase chromatography conditions settling (non-UV products)
  • Titration
  • Reaction media analysis (LC/MS coupling)
Low Voltage electron microscopes LVEM5
 
 
 
 
 
 
 
 
 
 
 
 
 
 
electron microscope