Frédéric Joliot Institute for Life Sciences - On the same theme

Early auditory environment influences superior temporal sulcus depth in the neonatal period

Mon, 23 Feb 2026 11:00:00 GMT

A team from NeuroSpin investigated the impact of contrasting auditory environments on the morphology of the superior temporal sulcus (STS) in preterm newborns. By showing that exposure to music is associated with a deeper STS, the authors suggest that early auditory experience influences the structural development of temporal brain regions.

Opening the BBB to Deliver Drugs to the Brain: Removing Noise Signals to Optimize Focused Ultrasound Pressure Control Protocol

Wed, 14 Jan 2026 11:00:00 GMT

Des équipes du SHFJ, de NeuroSpin et du CEA-Jacob optimisent leur stratégie d'ouverture de la barrière hémato-encéphalique par ultrasons focalisés (FUS). Leur nouveauté : un algorithme masquant la cavitation extracrânienne induite par les muscles temporaux épais, particulièrement chez les grands mâles primates, qui vient masquer le signal dans la région d'intérêt.

3D spirometry using functional lung MRI : investigating respiratory dynamics in a reliable and non-invasive manner.

Mon, 12 Jan 2026 11:00:00 GMT

A team from SHFJ has developed an original method of 3D spirometry using pulmonary magnetic resonance imaging in a cohort of volunteers breathing freely. This approach has revealed the existence of common patterns among individuals that depend mainly on gravity. This is a step towards a regional pathophysiological characterisation of respiratory diseases.

Using Light to Switch Off the MRI Signal of Micellar Probes for Diagnostic Purposes

Fri, 05 Dec 2025 11:00:00 GMT

Researchers at the SCBM and BAOBAB have developed a new version of their nanometric micellar vector designed for fluorine-19 magnetic resonance tumor imaging. This version is intended to enhance MRI contrast by switching off the signal on demand in certain areas, while preserving it in pathological regions to be imaged.

Seismic-wave physics for diagnosing brain tumors with passive MRI elastography

Wed, 26 Nov 2025 11:00:00 GMT

Researchers at SHFJ and NeuroSpin applied a passive MRI elastography sequence to patients with brain tumors. This non-invasive approach provided information on tumor stiffness and nature, and could support early detection, surgical planning, and treatment monitoring.

Quand les modèles mathématiques donnent un coup de pouce à l’IRM fonctionnelle pour mieux définir et prédire les états de conscience

Thu, 09 Oct 2025 10:00:00 GMT

Deux études récentes menées par des équipes de NeuroSpin proposent d’appliquer des méthodes combinant des modèles mathématiques d’analyse de données à l’IRM fonctionnelle pour mieux modéliser les connectivités fonctionnelles du cerveau.

Ultrasound to counteract the cerebral effects of exposure to a neurotoxic agent

Thu, 28 Aug 2025 10:00:00 GMT

Researchers from BioMaps (SHFJ), NeuroSpin, and the french IRBA developed an innovative approach using focused ultrasound to improve brain delivery of an antidote, oxime, following exposure to an organophosphorus neurotoxic agent in a murine model.

Monitoring microstructural and functional brain development in preterm and full-term infants using multimodal MRI

Mon, 04 Aug 2025 10:00:00 GMT

A team from NeuroSpin studied the microstructural and functional connectivity profiles of infants’ brains to understand how these characteristics evolve and relate to each other during early neurodevelopment. The results indicate that connectivity, which is altered by prematurity, strengthens with maturation, and that the associated networks become increasingly similar.

Statistical learning beyond words in human neonates

Tue, 22 Jul 2025 10:00:00 GMT

Ghislaine Dehaene's team (NeuroSpin) carried out EEG experiments on neonates to find out whether statistical learning was a mechanism dedicated solely to language acquisition. By exploiting the speaker identity and phonemes, the researchers conclude that statistical learning mechanisms are universal and not limited to linguistic characteristics.

Correlation between neuroinflammation and epileptogenic zone in drug-resistant focal epilepsy

Tue, 15 Jul 2025 10:00:00 GMT

A study by SHFJ researchers has established a strong correlation between biomarkers of neuroinflammation, revealed by original PET imaging, and intracranial electroencephalographic recordings of epileptogenic activity. This offers hope for drug-resistant patients who are candidates for surgery.

A promising drug candidate for the treatment of neonatal hypoxic-ischemic encephalopathy

Thu, 26 Jun 2025 10:00:00 GMT

Researchers from the SPI (DMTS) and the Women & Infants Hospital in Providence have laid the molecular basis for the neuroprotection of a purine derivative in a preclinical model of neonatal hypoxic-ischemic encephalopathy (HIE). The promising results support the development of this drug candidate to treat HIE in neonates.

How does our brain remember the duration of events?

Mon, 05 May 2025 10:00:00 GMT

A behavioural study conducted by a NeuroSpin team assessed the brain's processing of duration in working memory by having participants memorise a sequence of time intervals and then reproduce the duration of each interval. The results suggest that the brain processes the duration of each event as separate information.

Devenir adolescent après avoir eu un AVC à la naissance : la croissance cérébrale dépend-elle du sexe ?

Fri, 18 Apr 2025 10:00:00 GMT

Une étude dirigée par une équipe de NeuroSpin confirme la vulnérabilité spécifique du cerveau du bébé masculin après un AVC autour de la naissance.

Troubles psychiatriques : quelle IA choisir pour mieux analyser les images IRM du cerveau ?

Thu, 27 Feb 2025 11:00:00 GMT

Une étude comparative menée par des chercheurs de l’UMR BAOBAB/NeuroSpin en collaboration avec le LTCI (Télécom Paris) explique pourquoi l’apprentissage profond est plus performant que l’apprentissage automatique standard en neuroimagerie et souligne le potentiel de l’apprentissage par transfert.

IRM à ultra haut champ : Un signal sur bruit localement amélioré par un réseau de capteurs de surface ciblant le cortex des lobes temporaux

Thu, 30 Jan 2025 11:00:00 GMT

Une équipe de NeuroSpin en collaboration avec Multiwave Technologies a conçu et développé une antenne de réception pour l’IRM Iseult 11,7 T ciblant uniquement les lobes temporaux, une région d’intérêt pour les neuroscientifiques.

QSM4SENIOR : une cartographie quantitative inédite de la charge en fer des noyaux centraux du cerveau humain dans le vieillissement naturel

Tue, 26 Nov 2024 11:00:00 GMT

Les premières données du projet QSM4SENIOR, porté par des équipes de NeuroSpin et de la société VENTIO, ont été publiées dans Frontiers in Neuroimaging. Elles permettent de dresser une cartographie très précise de l’évolution de la charge en fer au cours du vieillissement cérébral normal, une aide précieuse pour les scientifiques spécialistes des maladies neurodégénératives.

QSM4SENIOR : unprecedented quantitative mapping of the iron load in the central nuclei of the human brain during natural ageing

Tue, 26 Nov 2024 11:00:00 GMT

The first data from the QSM4SENIOR project, led by teams from NeuroSpin and VENTIO, have been published in Frontiers in Neuroimaging. They provide a highly accurate map of changes in iron levels during normal brain ageing, a valuable aid for scientists specialising in neurodegenerative diseases.

A comparative analysis of the chimpanzee and human brain superficial structural connectivities

Fri, 22 Nov 2024 11:00:00 GMT

A team from NeuroSpin has proposed a classification of the morphology of short white matter bundles (SWMBs) in human and chimpanzee brains. A wide variety of shapes was observed, as well as differences. This study provides valuable information on SWMB morphology and its potential implications for human cognitive development

IBC 3, high-resolution mapping of cognitive functions in response to naturalistic stimuli

Wed, 30 Oct 2024 11:00:00 GMT

Several NeuroSpin researchers have taken part in the Individual Brain Charting (IBC) project, aimed at creating a precise map of the cognitive functions of the human brain. In this third phase, they are using the Fast Shared Response Model to analyze large-scale fMRI data and model responses to natural stimuli involving the visual, auditory and language systems.

Iseult : après les images, la publication scientifique

Mon, 28 Oct 2024 11:00:00 GMT

L’équipe de NeuroSpin en charge de l’acquisition des premières images de cerveau de volontaires à 11,7 teslas a publié dans Nature Methods les détails de son protocole d’étude exploratoire menée à ce champ magnétique inégalé.

SplineBeam : un algorithme réaliste et rapide pour prédire les champs de pression des ultrasons.

Thu, 24 Oct 2024 10:00:00 GMT

Les applications thérapeutiques des ultrasons sont nombreuses, notamment en neurologie. Prédire en temps réel le champ de pression acoustique à appliquer est indispensable. C’est ce que permet de faire l’algorithme SplineBeam développé par une équipe du SHFJ en collaboration avec le CEA-List, NeuroSpin et le CHU Grenoble-Alpes.

Study of subcortical neuromodulatory systems alteration in Alzheimer's disease and related disorders

Wed, 16 Oct 2024 10:00:00 GMT

A team from GHU Paris and SHFJ has used brain MRI to study the integrity of the locus coeruleus and nucleus basalis of Meynert in patients with early-onset Alzheimer's disease (AD), age-related TDP-43 encephalopathy (LATE) and fronto-temporal dementia (FTD). Both structures are altered in early AD, LATE and probably FTD, making these neuromodulatory areas potential therapeutic targets

Studying functional brain connectivity to understand the different emotional states in bipolar disorder

Mon, 30 Sep 2024 10:00:00 GMT

A study conducted by NeuroSpin researchers reveals abnormalities in functional brain connectivity in the sub-nucleus region of the amygdala (emotion center), in patients with bipolar disorder. These anomalies, which depend on whether the patient is depressed or manic, are potential biomarkers of interest.

PET imaging evaluation of the central effects of a drug-candidate to aid smoking cessation

Thu, 29 Aug 2024 10:00:00 GMT

A BioMaps team has used PET imaging to monitor glucose metabolism as a marker of the cerebral impact of smoking cessation, as well as the effects of a promising drug-candidate for the treatment of such cessation. By revealing the restoration of normal activity in the brain area associated with craving, these results offer hope for smoking cessation in humans

Associative learning explains human sensitivity to complex auditory sequences

Wed, 17 Jul 2024 10:00:00 GMT

A NeuroSpin team analyzed the MEG response of volunteers exposed to auditory sequences organized in network. Finding that participants' brain activity was sensitive to the structure of the network, it concluded that learning the structure of auditory sequences involves a single cognitive process, associative learning.

Cerebellum and cognitive function: anatomical correlations revealed from a large transdiagnostic sample

Fri, 05 Jul 2024 10:00:00 GMT

A collaborative study led by NeuroSpin researchers analyzed anatomical MRI images of 662 young subjects from the Healthy Brain Network cohort, to map different features of cognitive function linked to cerebellar structure. It shows that there is a complex association between key cognitive functions and particular lobules of the cerebellum.

A world premiere: the living brain imaged with unrivaled clarity thanks to the world’s most powerful MRI machine

Tue, 02 Apr 2024 10:00:00 GMT

The CEA is revealing a series of in vivo human brain images acquired with the Iseult MRI machine and its unmatched 11.7 teslas magnetic field strength. This success is the fruit of more than 20 years of R&D as part of the Iseult project, with one pillar goal being to design and build the world’s most powerful MRI machine. Its ambition is to study healthy and diseased human brains with an unprecedented resolution, allowing us to discover new details relating to the brain’s anatomy, connections, and activity.

Towards a neurodevelopmental model for the prediction of psychotic transition

Thu, 21 Mar 2024 11:00:00 GMT

A NeuroSpin team has built a predictive model for the onset of psychosis using a combination of supervised learning analyses and a model of neuroanatomical age, based on neuroimaging data from healthy subjects and those at risk of psychotic transition.

What do cognitive neurosciences have to say about our perception of time?

Tue, 27 Feb 2024 11:00:00 GMT

A team from NeuroSpin has recently published 3 papers that address the question of how we perceive time from a cognitive neuroscience perspective, using real-life temporal experiments, laboratory experiments and MEG brainwave measurements indicative of the passage of time, and that shed light on how the brain constructs our experience of lived time.

Innovative methodological developments for the emergence of ultra-high field MRI in clinical research

Mon, 19 Feb 2024 11:00:00 GMT

Researchers at NeuroSpin have recently published 3 articles in Magnetic Resonance in Medicine on their technological and methodological developments that will help meet the challenges of ultra-high field MRI for tomorrow's medical brain imaging.

First complete atlas of chimpanzee brain connectivity

Mon, 12 Feb 2024 11:00:00 GMT

NeuroSpin researchers map chimpanzee brain structural connectivity for the first time using diffusion MRI data. New image processing enabled them to create two atlases of deep and superficial white matter connectivity. A step towards a better understanding of the evolution of the hominid brain.

Where and how is the representation of quantities generated in the brain? Study using ultra-high field functional MRI

Wed, 31 Jan 2024 11:00:00 GMT

In a study published in Nature Communications, researchers from UNICOG and BAOBAB use high-field functional MRI to reveal the brain areas where the representations of quantities generated by a mental arithmetic operation are encoded.

Dyslexia: some of the devices sold to make reading easier are not effective

Sun, 28 Jan 2024 11:00:00 GMT

Devices such as lights and strobe glasses that are supposed to make reading easier for dyslexic people actually have no impact. These are the findings of a study conducted by a team from UNICOG (NeuroSpin) and published in the journal Proceedings Royal Society.

Validation of a new elasticity biomarker for biological tissue diagnosis

Wed, 24 Jan 2024 11:00:00 GMT

SHFJ researchers have validated the use of a new biomarker, the nonlinear shear modulus, to measure the elasticity of biological tissues, by comparing results obtained using echography with those obtained using MRI imaging and digital simulation. This biomarker is of particular interest for the diagnosis of certain breast cancers.

38 million euros secured for EBRAINS

Thu, 11 Jan 2024 11:00:00 GMT

Neural representation of uncertainty: towards a consensus?

Fri, 17 Nov 2023 11:00:00 GMT

In a review article published in Nature Neuroscience, researchers, including Florent Meyniel from UNICOG (NeuroSpin), show that the two dominant approaches to the neural representation of uncertainty are complementary and would benefit from being used synergistically.

Characterization of low-frequency neuronal oscillations in human magnetoencephalography

Wed, 18 Oct 2023 10:00:00 GMT

NeuroSpin researchers show that spontaneous neuronal oscillations in the 'delta' frequency band (0.5-3 Hz), the wave of unconscious states, can be observed in awake human volunteers using MEG. A step towards characterizing underlying physiological signals?

IRM : effets transitoires des ultra hauts champs sur le système vestibulaire

Fri, 06 Oct 2023 10:00:00 GMT

Des chercheurs de NeuroSpin, en collaboration avec NeuroPSI montrent que l’effet des ultra hauts champs magnétiques sur l’appareil vestibulaire de souris est transitoire.

Understanding the relationship between cerebellar structure and social abilities in young subjects with autism-related symptoms

Tue, 12 Sep 2023 10:00:00 GMT

A collaborative study by NeuroSpin researchers, using anatomical MRI data and a dimensional approach in 850 subjects from the Healthy Brain Network cohort, shows how the social skills of these children and adolescents are linked to the structure of their cerebellum

Rentrée « en mode kick-off » pour l’équipe MIND

Mon, 11 Sep 2023 10:00:00 GMT

Le 07 septembre, l'équipe MIND organisait son kick-off meeting, symbolisant la volonté commune de sestutell es, CEA et Inria, de consolider et de créer des synergies en intelligence artificielle et machine learning pour les neurosciences.

kick-off meeting for the MIND team

Mon, 11 Sep 2023 10:00:00 GMT

On 07 September, the young MIND team organised its kick-off meeting, symbolising the shared desire of its two supervisory administrations, the CEA and Inria, to consolidate and create synergies in artificial intelligence and machine learning for neuroscience.

L’IA pour l’IRM à haut champ : les multiples pistes développées par l’équipe MIND pour ne plus choisir entre temps et qualité de l’image

Wed, 30 Aug 2023 10:00:00 GMT

Longitudinal monitoring of tauopathy in PET imaging to better understand the various modalities of clinical evolution of Alzheimer's disease

Wed, 02 Aug 2023 10:00:00 GMT

A joint team from GHU Paris and BioMaps (SHFJ) conducted a 2-year longitudinal study of 27 people with Alzheimer's disease, tracking the progression of tau pathology measured by PET imaging, of cortical atrophy using MRI, and their links with cognitive decline.

Comment le cerveau intègre-t-il efficacement les informations visuelles et auditives de la parole ?

Tue, 25 Jul 2023 10:00:00 GMT

Une étude dirigée par une équipe d’UNICOG montre que le cerveau humain optimise l’intégration des informations auditives et visuelles de la parole à différentes échelles anatomiques et fonctionnelles, grâce à un ensemble de réseaux neuronaux hiérarchiquement imbriqués et synchronisés.

The "rabbit motif" in 18F-DOPA PET imaging for a simplified diagnostic evaluation of parkinsonian syndromes

Tue, 23 May 2023 10:00:00 GMT

BioMaps researchers compared the diagnostic performance of the rabbit visual pattern observed in 18F-DOPA PET imaging with the standard procedure approved by the international nuclear imaging societies for the diagnosis of parkinsonian syndromes in PET/MRI and obtained encouraging results, which may validate the clinical utility of such a model

Characterization of the neural representation of confidence during probabilistic learning

Wed, 10 May 2023 10:00:00 GMT

Using a dynamic probability learning task and high-field (7T) fMRI, a NeuroSpin team identifies regions in parietal and frontal cortex involved in the neural representation of prediction confidence during human learning

Mise en exploitation de l’IRM 11.7 T Iseult : revue de détails

Fri, 28 Apr 2023 10:00:00 GMT

La mise en exploitation de l’IRM 11.7 T Iseult en 2021 a couronné près de 20 ans de recherche et développement du CEA. Dans un article publié dans le journal Magnetic Resonance Materials in Physics, Biology and Medecine, Nicolas Boulant et Lionel Quettier, chefs du projet Iseult pour les instituts Joliot et Irfu du CEA, passent en revue les détails de cette mise en service.

Combining neuroanatomical markers to strengthen the diagnosis of fetal alcohol spectrum disorder

Mon, 13 Mar 2023 11:00:00 GMT

By analyzing brain imaging data, researchers from InDEV (NeuroSpin / UMR NeuroDiderot) have identified recurrent abnormalities in subjects with fetal alcohol syndrome, the combination of which could have a particularly interesting diagnostic value for non-syndromic forms of fetal alcohol spectrum disorders.

Genetic variations in evolutionarily acquired DNA regulatory regions affect the morphology of certain sulci in the human cerebral cortex

Mon, 27 Feb 2023 11:00:00 GMT

Using UK Biobank imaging-genetics data, a collaborative study led by NeuroSpin found that variation in genomic regions, known as enhancers, could affect the morphology of cortical sulci and be associated with the evolution of locomotion in primates and bipedalism in our hominin ancestors.

Anatomical atypia in autistic people ? Fine morphological analyses contradict the results of the last decade

Mon, 06 Feb 2023 11:00:00 GMT

By studying the morphology of the cerebellar gray matter, an international consortium coordinated by NeuroSpin researchers concludes that there are no anatomical atypia in the cerebellum of people with autism.

ERC Starting Grant for Timo van Kerkoerle at NeuroSpin!

Tue, 22 Nov 2022 11:00:00 GMT

Timo van Kerkoerle, researcher at NeuroSpin, is one of the 408 winners of the prestigious ERC Starting Grant 2022 call of the European Research Council. Another European success for the Institute.

MRI: signal-to-noise ratio at high field strengh, when experiment validates theory

Thu, 17 Nov 2022 11:00:00 GMT

A collaboration led by a METRIC team (BAOBAB/NeuroSpin) has undertaken to measure the signal-to-noise ratio (SNR) in MRI at the centre of a spherical phantom at different magnetic field strengths (B0). Their data confirm the theories that SNR increases with approximately the square of B0.

Studying low-concentration metabolites in the brain with CEST-linescan

Tue, 15 Nov 2022 11:00:00 GMT

NeuroSpin researchers, in collaboration with Iramis and the Università Statale di Milano, have developed a CEST magnetic resonance spectroscopy sequence that allows them to detect and confirm the presence of three dipeptides in the brain and skeletal muscle of adult rats and thus to consider future studies of their physiological role.

First results of the "Confined time" study released in Blursday, a resource to understand our perception of time during lockdown

Mon, 19 Sep 2022 10:00:00 GMT

The participative study on our time perception during the confinement, led by Virginie van Wassenhove (NeuroSpin), provides the first open database, Blursday, which analyzes the nature of the alterations in our relationship to time during physical and social distancing, as we experienced during the Covid-19 pandemic.

Specificity of reading and face recognition cerebral circuits during reading acquisition

Mon, 12 Sep 2022 10:00:00 GMT

By measuring fMRI responses to written words, faces, houses and checkerboards in three groups of children, pre-readers and beginning readers aged 6 and advanced readers aged 9, a team from UNICOG (NeuroSpin) shows that reading acquisition recycles and specializes a pre-existing but plastic visual circuit connected to language areas.

Predicting all cognitive activities from images of the functionning brain, it's possible

Thu, 30 Jun 2022 10:00:00 GMT

A NeuroSpin team succeeded in decoding a large set of human mental processes by training neural networks to predict cognitive labels from a cognitive atlas and by leveraging the data set of NeuroVault, a web-based database for collecting and sharing statistical maps of the human brain.

New generation of dielectric pads for ultra high field MRI imaging

Tue, 07 Jun 2022 10:00:00 GMT

To address the problem of ultre high field MRI signal loss in certain regions of the human body, a collaboration involving the CEA-Joliot, the CEA-Iramis, the Fresnel Institute and Multiwave Imaging has led to the development of a new generation of simple and inexpensive silicon carbide-based pads. The new composition makes the pads invisible to MRI and prolongs their performance when compared to existing solutions.

First atlas of anatomical brain connectivities in quail!

Tue, 31 May 2022 10:00:00 GMT

The expertise of NeuroSpin in diffusion MRI has allowed to establish the first atlas of the anatomical connectivities of the Japanese quail brain at a resolution of 150 m in three dimensions.

What if the shape of the early brain sulci could predict certain pathologies?

Fri, 20 May 2022 10:00:00 GMT

Neurospin researchers conducted a longitudinal brain imaging study in very premature infants to analyze the variability of the shape of the central sulcus early in its development and its functional implications.

Multisensory integration may be a matter of temporal coincidences

Wed, 18 May 2022 10:00:00 GMT

A team at NeuroSpin, in collaboration with the University of Ulm (Germany), published a study in Nature Communications that suggests the existence of multisensory correlation detectors in the human brain.

Object detection facilitates segmentation of rare brain tumors in MR imaging

Thu, 05 May 2022 10:00:00 GMT

A study led by NeuroSpin researchers proposes an optimized delineation of rare brain tumors, based on a combined approach of object detection and deep learning segmentation in tumor images, a key step in the characterization of cancers.

MRI: the SPARKLING algorithm, even more sparkling!

Thu, 28 Apr 2022 10:00:00 GMT

NeuroSpin researchers propose a new version of their compressed MRI acquisition algorithm, SPARKLING, extended to 3D imaging. Their method reduces acquisition time by a factor of 20 for T2*-weighted scans without compromising image quality.

Hybrid PET/MRI imaging, a unique examination to improve the detection of epileptogenic lesions

Tue, 05 Apr 2022 10:00:00 GMT

A team from BioMaps (SHFJ), in collaboration with several hospital groups, shows that hybrid PET/MRI imaging significantly improves the detection of epileptogenic foci and, consequently, the outcome of surgical treatment of epilepsy.

The New York Times is interested in the studies on the sensitivity to geometry conducted at NeuroSpin

Thu, 31 Mar 2022 10:00:00 GMT

In an article in the New York Times, Stanislas Dehaene (NeuroSpin director) and Mathias Sablé-Meyer (PhD student) discuss recent results obtained in collaboration with the Collège de France, the CNRS and the University of Paris 8 that show that humans have a universal capacity to understand abstract geometric concepts.

Deep brain stimulation of the thalamus restores signatures of consciousness

Sat, 26 Mar 2022 11:00:00 GMT

Using fMRI and EEG, NeuroSpin and ICM researchers show that deep brain stimulation of the central part of the thalamus restores the richness of brain activity specific to consciousness, which is "switched off" in an anesthetized non-human primate. This work paves the way for clinical studies in patients with consciousness disorders.

7T Sodium MRI confirms early metabolic damage in Alzheimer's disease

Mon, 07 Mar 2022 11:00:00 GMT

7T Sodium MRI may well prove increasingly useful in the study of physiological processes in inflammatory and neurodegenerative diseases and brain tumors. An example is a study on Alzheimer's disease, led by a NeuroSpin team.

Brain aging: European funding to evaluate an early biomarker

Wed, 02 Mar 2022 11:00:00 GMT

The QSM4SENIOR project, led by NeuroSpin and the company VENTIO, aims at developing an original early biomarker of aging by using data from the SENIOR study of NeuroSpin. QSM4SENIOR has just been funded by the EOSC-Life.

AI: predicting simply and efficiently like the brain

Thu, 17 Feb 2022 11:00:00 GMT

Two researchers of UNICOG/NeuroSpin show that a gated recurrence model of neural networks would allow to make efficient and simple predictions, like our brain, in different environments. In addition to being biologically plausible, this model would be generalizable.

The genetic architecture of language functional connectivity revealed

Mon, 14 Feb 2022 11:00:00 GMT

Using data from the UK Biobank, the world's largest general population imaging-genetics cohort, a collaboration led by a team at BAOBAB (NeuroSpin) has identified genes involved in the genetic architecture of language functional connectivity. These genes could be a priority for studying natural language.

Signal optimization in very high field functional MRI: a matter of compromise?

Thu, 27 Jan 2022 11:00:00 GMT

A NeuroSpin team (BAOBAB) has tested a signal denoising method dedicated to very high field (7T) functional MRI. It is based on the weighted combination of images from each reception channel of the radio frequency coil, a combination that optimizes the stability of the signal over time.

Brain development and mental health in adolescents and young adults

Tue, 25 Jan 2022 11:00:00 GMT

A NeuroSpin team has exploited data on mental health and brain developmental disorders of subjects in the Healthy Brain Network cohort. It established a link between certain symptoms, precursors of possible mood disorders, and structural changes in the developing brain in more than 650 young people.

Minimal computational models accounting for emergence of a specific region underlying orthographic coding

Tue, 30 Nov 2021 11:00:00 GMT

Researchers from NeuroSpin designed, trained and tested biologically plausible artificial deep neural networks to identify pictures and written words. They show that these may suffice to account for emergence during reading acquisition of the visual word form area, a specific region underlying orthographic coding.

Multiparametric PET-MRI imaging: toward a biological characterization of tumors at the supervoxel level

Wed, 10 Nov 2021 11:00:00 GMT

A collaborative study led by BioMaps researchers (SHFJ) demonstrates that fully integrated quantitative multiparametric analysis of non-small cell lung cancer in hybrid 18F-FDG PET/MRI 3T imaging is clinically feasible and could enable biological characterization of tumors at the supervoxel scale.

The most powerful MRI scanner in the world delivers its first images!

Thu, 07 Oct 2021 05:00:00 GMT

September 2021, the 11.7 Tesla MRI of the Iseult project, the most powerful in the world for human imaging, has just unveiled its first images.

A combinatorial neural code for speech is present in the infant

Tue, 14 Sep 2021 10:00:00 GMT

Researchers at UNICOG (NeuroSpin) show, using a high-resolution electroencephalographic system, that speech, an extremely complex and variable acoustic signal, is perceived by infants as a sequence of stable and invariant segments through an encoding based on distinctive and orthogonal phonetic features, such as manner and place of articulation, which are secondarily combined into phonemes, such as ″b″ or ″m″.

Disentangle the neuronal and vascular components of the BOLD signal for an improved visualization of brain activity

Tue, 14 Sep 2021 10:00:00 GMT

Researchers at NeuroSpin have developed a deconvolution method to estimate from BOLD fMRI data the coupling between neuronal activity and blood flow, the characteristic signals of neuronal activity and the associated brain areas. The work was published in NeuroImage.

Automatic recognition of brain "lines"

Mon, 23 Aug 2021 10:00:00 GMT

Researchers at NeuroSpin (CEA-Joliot) propose to automate the classification and recognition of folding patterns on the surface of the cortex that may be related to the occurrence of psychiatric diseases or cognitive disorders using artificial intelligence algorithms. A path towards deciphering the "lines" of the brain.

Diffusion MRI characterizes radiation-induced neurological impairments

Thu, 24 Jun 2021 10:00:00 GMT

A team comprising iRCM (CEA-Jacob) and NeuroSpin (CEA-Joliot) researchers analyzed the consequences of irradiation on brain development and neurogenesis in a preclinical model. That work, published in Radiation Research, lays a path for the use of diffusion imaging for the early detection of neurological abnormalities resulting from different types of stress.

Characteristics of the initial symptoms of Alzheimer's disease in young patients

Thu, 10 Jun 2021 10:00:00 GMT

Researchers from BioMaps (SHFJ) and the Department of Memory and Language Neurology (Ste Anne's Hospital) studied the early clinical signs of Alzheimer's disease (AD) reported by young patients (< 62 years old) compared to those reported in classic AD of the elderly (> 65 years old). They show that these signs are misleading and often appear in the professional context.

PET imaging reveals the neuropharmacology of buprenorphine

Wed, 05 May 2021 10:00:00 GMT

Researchers at BioMaps (SHFJ) have succeeded in determining the interaction dynamics of buprenorphine, an opioid drug with a particularly complex pharmacology, with its brain receptors in vivo. To do so, they developed an original PET imaging approach based on the use of the radiolabeled molecule (11C-buprenorphine).

WIKIBrainStem: a new ex vivo anatomical atlas of the human brainstem from ultra-high field MRI (11.7 T)

Wed, 28 Apr 2021 10:00:00 GMT

The Ginkgo team (BAOBAB / NeuroSpin), in collaboration with the Inserm iBRAIN U1253 unit (Tours), published in NeuroImage the first anatomical atlas of the human brainstem with at mesoscopic scaleresolution from extreme ultra-high field MRI. Freely available as a wiki, this atlas will be used in particular by neuroanatomists and neurosurgeons.

Humans Share an Exceptional Sense of Geometry

Fri, 23 Apr 2021 10:00:00 GMT

Research from CEA, Collège de France, CNRS and Université Paris 8 shows that humans share a universal ability to understand abstract geometric concepts. This human ability does not depend on age, culture or education, but does not exist in the non-human primates tested. PNAS has just published their results.

Brain sulci imaging and genetics: the UK Biobank cohort has spoken.

Mon, 19 Apr 2021 10:00:00 GMT

Researchers from NeuroSpin and CNRGH (Jacob Institute) have studied, on a genome-wide scale, the potential associations of haplotypes (set of variants located side by side on a chromosome) with the opening value of imaged brain sulci, indicator of brain aging, from the UK Biobank neuroimaging-genetics cohort.

Aloïse Mabondzo receives exceptional funding from NIH !

Mon, 29 Mar 2021 10:00:00 GMT

Aloïse Mabondzo, research director, head of the Neurovascular Pharmacology Group of the SPI (DMTS), co-founder and scientific director (CSO) of CERES BRAIN THERAPEUTICS, has just obtained funding of nearly one million US dollars from the prestigious National Institute of Health for his project « Neuroprotective Strategy: Novel Purine Derivatives for Neonatal Hypoxia-ischemia ».

A micellar probe for fluorine magnetic resonance tumor imaging

Thu, 04 Mar 2021 11:00:00 GMT

A SCBM (DMTS) team, in collaboration with researchers at NeuroSpin and I2BC, is describing micellar nanometric vectors targeting tumors that have been imaged by fluorine magnetic resonance imaging (MRI). The observed 19F signal made it possible to precisely delimit the volume of the tumor zone in a mouse model and to quantify the probe accumulated in the target tissue.

Metabolomics for the clinician and the development of a neuroprotective strategy in acute stroke

Thu, 04 Feb 2021 11:00:00 GMT

The TIRO team (SHFJ), in collaboration with the neurovascular clinicians of the Nice and Marseille University Hospitals, carried out analyses of the metabolome of cerebral clots at the origin of the occlusion of a cerebral artery responsible for a cerebral vascular accident (stroke). A pilot study that improved the understanding of the complex relationship between blood glucose levels and patients' functional prognosis.

Towards a transcranial echography

Tue, 19 Jan 2021 11:00:00 GMT

Jean-Luc Gennisson (BioMaps/SHFJ) coordinated, in partnership with the CEA-List (Sylvain Chatillon), the EchoBrain project (ATTRACT/H2020) aimed at adapting the digital tools developed by the List (CIVA platform) to significantly increase the quality of brain echography images, simple alternative compared to the methods (MRI, X-ray scanner) currently used for the diagnosis of strokes.

Launch of AROMA, a european project to exploit the full potential of NeuroSpin's future 11.7 T scanner.

Wed, 06 Jan 2021 11:00:00 GMT

AROMA, a FET-Open H2020 project, aims to develop the methodology necessary for the optimal operation of the future 11.7 T MRI being installed at NeuroSpin. This 5-year project, coordinated by Nicolas Boulant (NeuroSpin), with an overall budget of 3.6 million euros, involving six partners from five countries representing academia and industry, started on January 1, 2021.

Facebook challenge in AI: CEA researchers ranked 2nd

Fri, 11 Dec 2020 11:00:00 GMT

In the field of artificial intelligence, international competition is tough. So when researchers from CEA-Joliot and Irfu challenge start-ups and other companies specializing in AI, we cheer them on. Here’s a success story from the field of MRI reconstruction.

An atypical cerebral organization for language

Wed, 09 Dec 2020 11:00:00 GMT

Researchers from the Neurofunctional Imaging Group (GIN, NeuroSpin, Bordeaux) studied by functional MRI, the organization of the brain network of sentence processing in individuals "atypical" for language, i.e. with a major role of the right hemisphere.

CEA carries for France the EBRAINS infrastructure inscription on the ESFRI roadmap

Wed, 09 Dec 2020 11:00:00 GMT

EBRAINS (European Brain ReseArch INfrastructureS) is a european research infrastructure designed by the scientific community which, based on a set of state-of-the-art digital platforms, aims to answer the analysis and processing needs of large brain data sets. CEA carries for France EBRAINS inscription on the European Strategy Forum on Research Infrastructures roadmap, which was submitted in early September 2020.

Psychotic symptoms are linked with poor diffusion of information in the brain

Tue, 08 Dec 2020 11:00:00 GMT

A collaborative study by NeuroSpin suggests that psychosis and impaired conscious access may be closely related phenomena.

Towards greater accuracy in the measurement of temperature variations induced by MRI examinations

Wed, 18 Nov 2020 11:00:00 GMT

Researchers at NeuroSpin are proposing a new magnetic resonance thermometry method to increase the accuracy in the measurement of small temperature variations induced by MRI.

BRICON, a project of the Human Brain Project for NeuroSpin (UNICOG)

Thu, 29 Oct 2020 11:00:00 GMT

Theofanis Panagiotaropoulos (NeuroSpin) obtains funding from the Human Brain Project for BRICON (Brain Inspired Consciousness), a project of HBP's neuroscience activities.

A double ceramic probe to optimize magnetic resonance microscopy.

Mon, 26 Oct 2020 11:00:00 GMT

Researchers from the M-CUBE european consortium, together with a team from NeuroSpin, are demonstrating the possibility of imaging two samples by 17.2 T magnetic resonance microscopy (NeuroSpin imager), at a single acquisition time, using two coupled ceramic resonators (probes) that lead to a better signal-to-noise ratio compared to reference MRI probes.

Analysis of multitask functional MRI data for the establishment of a neurocognitive atlas of the human brain

Thu, 08 Oct 2020 10:00:00 GMT

In this study, NeuroSpin researchers leveraged the Individual Brain Charting (IBC) dataset, acquired by high-resolution functional MRI during the performance of behavioural tasks, to investigate the feasibility of individual mapping of the cognitive components underlying the tasks. They thus individualized six regions of interest in the language network and established their cognitive profile.

Functional neuroanatomy of number processing at high-resolution

Wed, 23 Sep 2020 10:00:00 GMT

NeuroSpin researchers used ultra-high field (7 Tesla) functional magnetic resonance imaging (fMRI) to better localize the processing and manipulation of numbers in the human brain. The results, which enrich our understanding of the functional organization of the intra-parietal sulcus, the cerebral center of digitization, are published in NeuroImage.

Towards a new generation of antennas for ultra-high field imaging of the brain

Tue, 22 Sep 2020 08:06:13 GMT

The European Commission once more places its trust on Multiwave company and its partners, Aix-Marseille Université , CEA and Université Catholique de Louvain to revolutionize ultra-high field magnetic resonance imaging of the brain.

Predicting brain age using a computer model

Mon, 14 Sep 2020 10:00:00 GMT

Researchers from the PARIETAL team (Inria/CEA) at NeuroSpin and the University of Zurich have developed a computer model capable of accurately determining brain age. This model could be used to combine different types of brain function tests to predict, for example, cognitive decline or depression.

Florent Meyniel, laureate of the prestigious "ERC Starting grant" call

Thu, 03 Sep 2020 10:05:00 GMT

On September 3, the European Research Council announced the names of the 436 winners of the ERC Starting Grant 2020 call. Florent Meyniel, CEA researcher at the NeuroSpin department of the Joliot Institute, is among them.