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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
A collaborative study by NeuroSpin researchers, using anatomical MRI data and a dimensional approach in 850 subjects from the Healthy Brain Network cohort, shows how the social skills of these children and adolescents are linked to the structure of their cerebellum
Researchers at BioMaps (SHFJ) and SPI (DMTS) have studied the pharmacokinetics of a novel immuno-radioligand targeting the endothelin A receptor (ETA), overexpressed in many cancers, particularly glioblastoma. The immunoPET imaging approach used in this study in a preclinical model confirms the theranostic potential of this antibody.
The TIRO laboratory of the SHFJ (Nice) identifies for the first time discriminating biomarkers of high-grade invasive breast tumors, using a non-targeted metabolomics approach performed on surgical specimens and cytoponctions from patients at different stages of malignancy.
A team from I2BC has shown that the Mediator of transcription from the yeast S.cerevisiae physically interacts with the chromatin remodeling complex, and that by co-localizing with this complex on DNA promoter regions, it contributes to chromatin organization favorable to transcription initiation.
Des chercheurs de l’I2BC ont contribué à une étude menée par l’Iramis qui dévoile le rôle des protéines dans la dispersion des microplastiques dans l’eau. Leurs résultats permettent d’imaginer de nouvelles stratégies low tech pour débarrasser l’eau de cette pollution.
Researchers at SPI (DMTS) have identified by mass spectrometry and bioinformatics analysis several biomarkers linked to the creatine transporter deficiency disorder (CTD) using two original models : mice with the clinical characteristics of CTD subjects and brain organoids derived from CTD patient cells.
SIMoS researchers have identified and characterised an animal toxin (A-CTX-Mila) as a ligand for angiotensin II receptors, which are involved in one of the signalling pathways targeted by antihypertensive drugs. A tool of choice for studying the cellular mechanisms controlled by these receptors.
In an article in the New York Times, Stanislas Dehaene (NeuroSpin director) and Mathias Sablé-Meyer (PhD student) discuss recent results obtained in collaboration with the Collège de France, the CNRS and the University of Paris 8 that show that humans have a universal capacity to understand abstract geometric concepts.
September 2021, the 11.7 Tesla MRI of the Iseult project, the most powerful in the world for human imaging, has just unveiled its first images.
The European Commission once more places its trust on Multiwave company and its partners, Aix-Marseille Université , CEA and Université Catholique de Louvain to revolutionize ultra-high field magnetic resonance imaging of the brain.
Le projet EXPERIENCE cherche à utiliser la réalité virtuelle pour améliorer la vie quotidienne en permettant de nouvelles formes d’interaction sociale et d’expression personnelle.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.
