To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
The mission of the European Research Council is to encourage the highest quality research in Europe through competitive funding and to support investigator-initiated frontier research in all disciplines on the basis of scientific excellence.
With the Neural-PROB project, Florent Meyniel seeks to understand how the human brain estimates and uses uncertainty and the impact of these mechanisms on our ability to adapt to change in an uncertain world. Part of the project aims to determine the factors that influence our adaptability, particularly in learning situations.
In the FastLabEx project, Davide Audisio will imagine and design a faster, less expensive and less polluting process for marking molecules during the preclinical and clinical testing phases (drug candidates), or in the environment (pesticides for example). The aim is to ensure that the marking is the last step of the process, by cutting the very strong bonds with the 12C with extremely efficient catalysts, which are replaced by the 14C.
With the NEUROSYNTAX project, Stanislas Dehaene aims to explain the brain mechanisms responsible for human abilities for language and abstraction, and to shed light on their ontogeny and phylogeny using behavioral measures, functional MRI, magnetoencephalography (MEG), electro-cortigraphy (ECOG) and "machine learning" techniques.
With the SLAB project, Alexandre Gramfort wishes to contribute to the development of the next generation of statistical models and algorithms for the exploitation of electrophysiology signals that provide information on brain function at the millisecond scale.
With BABYLEARN, Ghislaine Dehaene-Lambertz seeks to explain the specificities of the functional neural architecture that are critical for learning in humans from the very beginning of the cortical circuits.
UNIPAT is a project that complements the EXPAT project funded by an ERC Starting grant. With this "proof of concept" project, Nicolas Boulant proposes to establish the scientific validity, the technical feasibility and the market potential of radiofrequency solutions called "universal pulses".
SUPER-RESOL is a project that complements PHOTPROT, funded by an ERC Advanced (n° 267333) and is a direct consequence of it. With this "proof of concept" project, Bruno Robert and Rienk Van Grondelle propose to further improve the super-resolution confocal fluorescence microscopy method developed in PHOTPROT in order to patent it and to start contacting industrials.
The aim of EXPAT is to apply sophisticated control techniques to manipulate the nuclear spins efficiently with parallel transmission at ultra high field MRI on the state-of-the art 7 Tesla and the unique 11.7 Tesla MRI scanner that will be installed at NeuroSpin/CEA. By bringing a practical solution to parallel transmission at such high field strength, EXPAT will be a major breakthrough for MRI of the brain.
In order to clarify the principles and mental operations underlying the perception of time, the MINDTIME project of Virginie van Wassenhove focuses on a new theoretical framework for understanding how the human mind enables the temporal experience of "now".
With the PHOTPROT project, Bruno Robert and Rienk Van Grondelle aim to study the role of protein matrix dynamics in photosynthetic processes. To do so, they will develop advanced biophysical approaches and new spectroscopic techniques. Among these, a method capable of extracting very high resolution images from images obtained by conventional confocal fluorescence microscopy.
Stanislas Dehaene, aims to find, through the NEUROCONSC project, the limits of subliminal information processing, with the goal of clarifying the brain mechanisms of conscious processing and paving the way for clinical intervention studies in patients with consciousness disorders.
The TERNANOMED project, involving Bernard Rousseau (former head of SCBM), aims at developing terpenoid-based nanoassemblies to improve the treatment of severe diseases such as cancer, infectious diseases. The approach consists in linking a terpene (synthetic or natural) to a biologically active drug in order to obtain a bioconjugate able to self-assemble in water in the form of nanoparticles.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.