To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
NeuroSpin, directed by Stanislas Dehaene, is a research center for innovation in brain imaging, located on the CEA Paris-Saclay site. At NeuroSpin, physicists, mathematicians, neuroscientists and doctors join forces to develop synergistically the tools and models that will allow to better understand the functioning of the normal and pathological brain, before or after treatment. Focused on neuroimaging, the research conducted ranges from technological and methodological developments (data acquisition and processing) to preclinical and clinical neuroscience, including cognitive neuroscience.
NeuroSpin has four research units located at the Saclay site and one unit located in Bordeaux :
Using a dynamic probability learning task and high-field (7T) fMRI, a NeuroSpin team identifies regions in parietal and frontal cortex involved in the neural representation of prediction confidence during human learning
Using UK Biobank imaging-genetics data, a collaborative study led by NeuroSpin found that variation in genomic regions, known as enhancers, could affect the morphology of cortical sulci and be associated with the evolution of locomotion in primates and bipedalism in our hominin ancestors.
Researchers from the SHFJ, in collaboration with NeuroSpin, show that the use of focused ultrasound does not increase the therapeutic effects of cetuximab on glioblastoma although the opening of the blood-brain barrier is transiently effective.
By studying the morphology of the cerebellar gray matter, an international consortium coordinated by NeuroSpin researchers concludes that there are no anatomical atypia in the cerebellum of people with autism.
Timo van Kerkoerle, researcher at NeuroSpin, is one of the 408 winners of the prestigious ERC Starting Grant 2022 call of the European Research Council. Another European success for the Institute.
A collaboration led by a METRIC team (BAOBAB/NeuroSpin) has undertaken to measure the signal-to-noise ratio (SNR) in MRI at the centre of a spherical phantom at different magnetic field strengths (B0). Their data confirm the theories that SNR increases with approximately the square of B0.
NeuroSpin researchers, in collaboration with Iramis and the Università Statale di Milano, have developed a CEST magnetic resonance spectroscopy sequence that allows them to detect and confirm the presence of three dipeptides in the brain and skeletal muscle of adult rats and thus to consider future studies of their physiological role.
To carry out their activities, researchers of NeuroSpin have access to platforms, certified IBiSA and part of the National Infrastructures in Biology and Health: France Life Imaging (FLI) and NeurATRIS :
These instruments are open to the national or international scientific community, to academics or industrials. Do you want to
submit your project to NeuroSpin ?
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.