Team Leader
Louisa BARRÉ
barre@cyceron.fr
Description
The Laboratory for Methodological Developments in Positron Emission Tomography (LDM-TEP) is a structure based within the UMR 6301 CNRS-CEA-UCBN « Imaging and Therapeutical Strategies in Cerebral and Tumoral pathologies » (ISTCT), managed by Myriam Bernaudin and is located at Cyceron, a biomedical imaging platform in Caen (France).
LDM-TEP, managed by Louisa Barré, is a unique structure whose primary mission is research at the interface between chemistry and radiochemistry and biology to exploit and enlarge the scope of PET imaging. LDM-TEP focuses on the development of radiopharmaceuticals biomarkers for preclinical and clinical research.
Armored cells equipped with remote controlled synthesis PLCs.
@P.Stroppa/CEA | | |
Three undernoted themes:
- Innovative radiochemical approaches that involve positron emitters (sultones strategy, vectorisation of molecules,...) ;
- The development and study of novel radiotracers as potential radiopharmaceutical agents (NR2B NMDA receptors, opiates receptors, lymphoma or apoptosis) ;
- The introduction of clinical radiotracers for the benefit of the varied users within the GIP Cyceron (FLT, FMISO, AV-45,...).
For each of these three themes and, above all the latter, our team masters the disciplines of organic and analytical chemistry as well as radiochemistry and radiopharmacy. Our varied competences in the above fields allows (after automation), the transfer of radiopharmaceuticals to internal and external structures. The valorisation and application of our specificities in these areas allows the rapid clinical evaluation of promising radiopharmaceuticals.