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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
SIMoS team, in collaboration with Bicêtre Hospital, shows that certolizumab pegol, a pegylated monoclonal antibody fragment for anti-inflammatory use, is less likely to trigger an adverse immune response than the non-pegylated form.
Researchers from ICMMO* and ISMO**, in collaboration with a team from I2BC, show that the urea-decorated iron porphyrin catalysts they developed previously for the electro-catalysis of CO2, can be successfully employed in a photo-catalytic approach.
A collaborative study involving an I2BC team unveils the mechanism of autoinhibition of the human flippase ATP8B1, as well as its regulation by lipids and phosphorylation. The study provides a better understanding of the impact of flippase mutations responsible for intrahepatic cholestasis on its enzymatic activity.
Neurospin researchers conducted a longitudinal brain imaging study in very premature infants to analyze the variability of the shape of the central sulcus early in its development and its functional implications.
A team at NeuroSpin, in collaboration with the University of Ulm (Germany), published a study in Nature Communications that suggests the existence of multisensory correlation detectors in the human brain.
NeuroSpin researchers propose a new version of their compressed MRI acquisition algorithm, SPARKLING, extended to 3D imaging. Their method reduces acquisition time by a factor of 20 for T2*-weighted scans without compromising image quality.
The ptairMS software, developed in the framework of a collaboration led by the CEA-Joliot, allows the processing and analysis of proton transfer mass spectrometry data, an ideal method for the real-time study of volatile organic compounds (VOCs) present in exhaled breath.
To address the problem of ultre high field MRI signal loss in certain regions of the human body, a collaboration involving the CEA-Joliot, the CEA-Iramis, the Fresnel Institute and Multiwave Imaging has led to the development of a new generation of simple and inexpensive silicon carbide-based pads. The new composition makes the pads invisible to MRI and prolongs their performance when compared to existing solutions.
The expertise of NeuroSpin in diffusion MRI has allowed to establish the first atlas of the anatomical connectivities of the Japanese quail brain at a resolution of 150 m in three dimensions.
In an exploratory study, a team from SPI used mass spectrometry to analyze the gut microbiota profile of Covid-19 patients and to search for signature markers of SARS-CoV-2 gut infection using functional metaproteomics. These markers could be used to follow the evolution of the disease.
A study led by NeuroSpin researchers proposes an optimized delineation of rare brain tumors, based on a combined approach of object detection and deep learning segmentation in tumor images, a key step in the characterization of cancers.
A collaboration between the SHFJ and the UMR-S 1144 (University of Paris) shows that the deleterious effect of the buprenorphine/benzodiazepine combination would result from the combined action of each drug on its target.
A team from the I2BC has just demonstrated, using transient absorption spectroscopy, that the repair of UV-induced damage in DNA by a repair enzyme (6-4) photolyase occurs in two successive photoreactions.
Researchers from the SCBM have participated in the optimization of a bio-inspired catalyst anode developed by teams from IRIG (CEA, Grenoble). In particular, they have contributed to the fine control of the catalyst surface concentration.
In an article in the New York Times, Stanislas Dehaene (NeuroSpin director) and Mathias Sablé-Meyer (PhD student) discuss recent results obtained in collaboration with the Collège de France, the CNRS and the University of Paris 8 that show that humans have a universal capacity to understand abstract geometric concepts.
September 2021, the 11.7 Tesla MRI of the Iseult project, the most powerful in the world for human imaging, has just unveiled its first images.
The European Commission once more places its trust on Multiwave company and its partners, Aix-Marseille Université , CEA and Université Catholique de Louvain to revolutionize ultra-high field magnetic resonance imaging of the brain.
Le projet EXPERIENCE cherche à utiliser la réalité virtuelle pour améliorer la vie quotidienne en permettant de nouvelles formes d’interaction sociale et d’expression personnelle.
Agenda | Conference | PARIS, France
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.
