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To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
Within the Institute, the "Funding Research and Technology Transfer" team is at your disposal to identify the scientists and the skills you need to set up a joint project, to define the terms of a collaboration contract or study. Whether you are an academic, a SME or an industrialist, our team informs and advices you about the possibilities of consortium assembly, technology transfer, patent licensing or use of our platforms. The team is also at the disposal of the researchers of the institute to accompany them in achieving their valorization objectives.
In a study published in JBC, a team from I2BC/CEA-Joliot, in collaboration with the Beijing Botanical Institute (China), describes for the first time an intermediate state of the light-harvesting antenna of higher plants that provides a better understanding of the changes that take place at the molecular level during the activation of a plant's photoprotection mechanism.
Researchers at Baobab (NeuroSpin), in collaboration with the iRCM (Jacob Institute), have analyzed the consequences of irradiation on brain development and neurogenesis in a mouse model exposed in utero, during embryonic development. They show the interest of the non-invasive MRI approach for the early detection of neurological anomalies.
A team of the I2BC (LMB/SB2SM), in collaboration with the Institute of Biology (Freiburg University), discovered a posttranscriptional regulatory mechanism linking the expression of the cyanobacterial Orange Carotenoid Protein, related to photoprotection, directly and in an inverse fashion, to the synthesis of the light collector complexes (phycobilisomes), via a 3’ end-derived small RNA.
Researchers at I2BC/CEA-Joliot, in collaboration with the RPBS platform, have developed the third version of their InterEvDock server for structural modelling of protein-protein interactions. The server integrates new algorithms for exploiting sequence evolution information.
Teams from CEA-Iramis and CEA-Joliot (team "Genome transcriptional regulation /I2BC) have joined forces to develop and validate an innovative microfluidic-based system that automatizes cell culture over many generations. It enables with considerable time savings large-scale experiments to be carried out, which are essential for understanding the cellular mechanisms involved in DNA mutation events.
Researchers from BioMaps (SHFJ) and the Department of Memory and Language Neurology (Ste Anne's Hospital) studied the early clinical signs of Alzheimer's disease (AD) reported by young patients (< 62 years old) compared to those reported in classic AD of the elderly (> 65 years old). They show that these signs are misleading and often appear in the professional context.
Researchers from I2BC/CEA-Joliot in collaboration with teams from Institut Curie and IRCM/CEA-Jacob, lay the molecular basis to explain the dual role of the Mlh1-Mlh3 complex in DNA mismatch repair and, quite uniquely, in one of the key steps of genetic mixing during meiosis.
The European Commission once more places its trust on Multiwave company and its partners, Aix-Marseille Université , CEA and Université Catholique de Louvain to revolutionize ultra-high field magnetic resonance imaging of the brain.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.
