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Scientific result | Photosynthesis | Bio-inspired catalysis
A team from I2BC@Saclay, in collaboration with the CNRS (ICMMO, UPSud and ISM2, Aix-Marseille University) has shown that the use of a reversible electron acceptor, able to accept and transfer an electron, in place of a sacrificial electron donor optimizes efficient and clean photocatalysis reactions for the production of organic compounds of interest.
Using light energy and O2 for the direct chemical oxidation of organic substrates is a major challenge. A limitation is the use of sacrificial electron donors to activate O2 by reductive quenching of the photosensitizer, generating undesirable side products. A reversible electron acceptor, methyl viologen, can act as electron shuttle to oxidatively quench the photosensitizer, [Ru(bpy)3]2+, generating the highly oxidized chromophore and the powerful reductant methyl‐viologen radical MV+.. MV+. can then reduce an iron(III) catalyst to the iron(II) form and concomitantly O2 to O2.− in an aqueous medium to generate an active iron(III)‐(hydro)peroxo species. The oxidized photosensitizer is reset to its ground state by oxidizing an alkene substrate to an alkenyl radical cation. Closing the loop, the reaction of the iron reactive intermediate with the substrate or its radical cation leads to the formation of two oxygenated compounds, the diol and the aldehyde following two different pathways.
NT Vo, Y Mekmouche, T Tron, R Guillot, F Banse, Z Halime, M Sircoglou, W Leibl, A Aukauloo. A Reversible Electron Relay to Exclude Sacrificial Electron Donors in the Photocatalytic Oxygen Atom Transfer Reaction with O2 in Water. 2019 Angewandte Chemie Int. Ed. https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201907337
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