To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
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Europe | European ＆ international partnerships | Antibiotics | Biodetection | Biotechnology
Development of a rapid test for the detection of AntiMicrobial Resistance
The AMR DetecTool project is the continuation of the BL DetecTool project, already funded by EIT Health. The project aims to develop rapid antibiotic resistance detection tests. It is coordinated by Hervé Volland (LERI/SPI).
The spread of antibiotic-resistant bacteria is a growing threat to public health. In Europe, they are implicated in 426,000 infections in hospitals and are responsible for 33,000 deaths per year.This increase is notably due to i) the lack of rapid tests to identify the type(s) of resistant bacteria in a short period of time and ii) the lack of standardized strategies for the implementation of effective diagnostic procedures, within healthcare facilities, to fight antibiotic resistance.A solution was provided by an innovation, patented by the CEA, which allowed the direct detection in clinical samples, in less than 30 minutes, of β-lactamases, enzymes produced by certain resistant bacteria and which hydrolyze beta-lactam antibiotics. These detection tests were successfully validated in the BL-DetecTool project, which was previously funded by EIT Health in 2018. This project involved a consortium of six European partners: hospitals, universities, research institutes and the SME NG Biotech.The same consortium is now set to: i) expand the detection domain of this innovation ii) evaluate the impact of this innovation on potential economic and/or therapeutic gains iii) develop a knowledge portal on antibiotic resistance to help hospitals develop strategies to combat antibiotic resistance. The consortium is funded since January 1, 2020 and for 3 years by the EIT Health.
CONTACT CEA : Hervé Volland (firstname.lastname@example.org)
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.