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Institute | Structural biology


Published on 30 January 2023

The Institute for Integrative Biology of the Cell (I2BC) UMR 9198 is a “Unité Mixte de Recherche” (joint research unit ; UMR ) supported by both Université Paris-Sud, the CNRS and the CEA. The Institute regroup 80 teams of scientists, 15 technological facilities from 8 research units (CGM, IBBMC, IGM, ISV, LEBS, VMS, SB2SM, SBiGeM)
The Institute is in 3 research campus (Orsay Campus of the Université Paris Sud, Gif Sur Yvette Campus of CNRS, and Saclay Campus of CEA) with 14 buildings. All the I2BC activities will be join on the Gif Sur Yvette Campus in 2018.

Adress: Avenue de la Terrasse, Bâtiment 21,
91190 Gif-sur-Yvette Cedex



I2BC@Saclay Department of ​the Frédéric Joliot Institute for Life Sciences permanently receives and prepares approximately 120 doctoral students., directed by Thierry Meinnel, carries out research in Integrative Biology of the Cell around four thematic axes :

  • Maintenance, expression et evolution of genomes,
  • Cell compartimentation  transport,
  • Stress and adaptation, differentiation,

I2BC@Saclay Department is divided in two units : 

Integrative Biology and Molecular Genetics Unit (SBIGeM)
Bioenergetics, Structural Biology and Mechanisms Unit (SB2SM).


Exceptional facilities and platforms

Its Research Teams are all members of the Institute of Integrative Biology of the Cell (I2BC), a Joint research unit (UMR 9198), whose tutors are CEA, CNRS and Paris Sud University. Currently located on the site of Saclay, they will join all the staff of the I2BC in 2019 in a new building, on the CNRS campus of Gif-sur-Yvette.

To carry out their activities, researchers of I2BC@Saclay Department have access to research platforms certified IBiSA within ​the Frédéric Joliot Institute for Life Sciences:

PARi : RNA interference platform,
Biophysics : heavy optical and magnetic spectroscopies platform. This platform is part of the National Infrastructure in Biology and Health (INBS)
FRISBI : (Structural Integrated Biology), financed by the Programme of Investments for the Future (PIA)

Moreover, Research Teams have also access to the other I2BC platforms.